The innovation engine for new materials

Brendan Carroll


Franklin Elementary School

Grade Level: 


Teaching Position: 

Science Specialist


Joel Rothman


Molecular, Cellular and Developmental Biology


Pan Young Jeong

Research Project Year: 


Research Project Title: 

Activating a Protein in a Mutant C. elegans Phenotype

Research Project Description: 

This summer I worked Dr. Pan Young Jeong in Dr. Joel Rothman’s lab in the Molecular Cellular and Developmental Department at UCSB. This lab dedicates its time to researching the model organism C. elegans, a soil nematode.  This round worm is the focus of intense research around the globe and this is partially due to the fact that it was the first species to have had its entire genomic sequence mapped out. 

Our focus was on determining the minimal conditions required to activate a certain protein (pHS;CED-4::FLAG) in a phenotype of the worm in which this protein had been intentionally integrated. This specially engineered protein allows researchers to isolate and study the CED-4 protein and thereby determine the role it plays in the worm’s genetic development. Scientists know that CED-4 is a key player in apoptosis, programmed cell death, but Dr. Jeong is interested in finding out what other functions it might have in C. elegans development, including embryogenesis and as a cell cycle “checkpoint” . By the end of my internship we were able to identify some of the requirements needed to induce CED-4 activation in the mutants we’d been using. 

Research Project Attachments: 

PDF icon Carroll C elegans powerpoint3.pdf16.62 MB

Curriculum Project Year: 


Curriculum Project Title: 

To Boldly Go . . . and Return! Destination: Space - Elementary Lessons Designed to inspire young Engineers

Curriculum Project Description: 

The unit To Boldly Go . . . and Return has students imagining the challenges of reaching space and returning safely. This collection of lessons focuses on teaching children the Engineering Design Process.  With the Next Generation Science Standards now implementing engineering as a key set of skills for students, lessons giving students the opportunity to confront problems, design solutions and evaluate their results are valued and encouraged. Students plan and design various devices around the space theme and then test, observe and measure the performance of the vehicles they’ve constructed.  Specific projects include antacid rockets, rocket balloons, flight experimentation with a class-built wind tube, parachute design and materials, paper airplane design and a final assessment project of an emergency return vehicle.  Students will also compare the effect of changing a single variable when experimenting with their projects.

Curriculum Project Attachments: 

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