The innovation engine for new materials

Jesse Kasehagen

Jesse Kasehagen


Santa Barbara Middle School

Grade Level: 

Junior High

Teaching Position: 

General Science


Kevin Plaxco




Adriana Patterson

Research Project Year: 


Research Project Title: 

Characterizing E-DNA scaffold biosensors for detection of antibodies in whole blood

Research Project Description: 

The advent of a diagnostic point-of-care device would substantially benefit healthcare systems worldwide. The development has proven to be difficult because there are very limited biosensors that achieve specific detection of macromolecules in complex media to date. The E-DNA scaffold architecture has demonstrated to be sensitive, specific and robust platform on which the development of macromolecule detection (such as antibodies) in real world samples has become possible. By using a specialized blocking solution, we have demonstrated the ability to detect a specific antibody in a complex medium such as undiluted whole blood in under an hour with little interference.

Research Project Attachments: 

Curriculum Project Year: 


Curriculum Project Title: 

Examples of open source technology in the science classroom

Curriculum Project Description: 

This project is an exploration of emerging hardware and software projects which share a common theme of being “open source” projects.  Along with being generally innovative and engaging, open source projects are communal in their development and relatively low cost in their implementation.  Developed and applied in this curriculum project is an interactive exercise using student-made graphite potentiometers, arduino sensors and the open-source educational software program “ManyLabs”.  Two separate “Sensor Circuits” lessons were also investigated using ManyLabs and “LittleBits” hardware.  Another direction briefly explored in this project is the low-cost open-source CNC hardware to conduct microscopy projects and as an autosampler in the classroom.

Curriculum Project Highlight:

Exploring Graphite Paint Potentiometers


Curriculum Project Attachments: 

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