The innovation engine for new materials

Megan Nesland


Anacapa School

Grade Level: 

High School

Teaching Position: 

Lead Science Teacher


Galen Stucky


Chemistry and Biochemistry


Tracy Chuong

Research Project Year: 


Research Project Title: 

Nanoparticles and Blood Coagulation: Measuring the Effect of Silica Nanoparticles on Clot Time of Human Plasma

Research Project Description: 

Blood loss following trauma is the 3rd leading cause of death in the United States. Current technology, such as QuikClot, effectively encourages clotting in external wounds, but leads to inflammation due to use of non-biocompatible materials. This study addresses the effectiveness of Silica Nanoparticles (SNP) at reducing clot time of human plasma for potential later use as an injectable, internal blood coagulant. This study uses real-time fluorescence and microscopy to track changes in clotting time with varying concentrations and delivery mechanisms of SNP. In solution, the SNP was found to encourage clotting at concentrations at or above .125mg/mL. In pellet form, the SNP seems to encourage clotting, but was not quantifiable using the detection methods at this time.  

Research Project Attachments: 

PDF icon MRLRET-bloodCoag2.pdf9.67 MB

Curriculum Project Year: 


Curriculum Project Title: 

Nanotechnology: What’s the Big Deal with the World’s Smallest Technology?

Curriculum Project Description: 

This curriculum introduces students to the field of nanotechnology, a growing field in science with a wide array of potential applications. It supplements the high school science curriculum and can be adapted into a variety of classrooms, including biology or chemistry, while developing inquiry skills and the ability of students to produce and support claims. The curriculum guides students through three essential questions: What is nanotechnology, how does it work and for what is it used?  Students investigate concepts of scale, derive the importance of surface area in nanotechnology through various engaging activities and demos, and explore a variety of applications of nanomaterials.  Culminating lessons include investigations of medical applications of nanoparticles including a mini-activity based on a research project on internal blood clotting and a “Build a Particle” activity in which students design their own nanoparticle to solve a specific problem such as cancer, multiple sclerosis, arthritis, asthma or antimicrobial resistance.

Curriculum Project Attachments: 

PDF icon M_Nesland_RET2-workshopPresentation.pdf10.39 MB
File 1. Nanotechnology Intro.docx96.92 KB
File 2. Nanotechnology Curriculum Map.docx106.85 KB
Office spreadsheet icon 3. Nanotechnology Unit Layout.xls37.83 KB
File 4. Nanotechnology Resources of Interest.docx78.03 KB
File 5 PreUnit Assessment-Nanotechnology Unit.docx57.63 KB
File 6 PostUnitAssessment-Nanotechnology Unit.docx58.43 KB
File Lesson1.1a NanoYou VideoNotes.docx49.17 KB
File Lesson1.1a- Teacher Guide NanoYou Video.docx122.92 KB
File Lesson1.1b- Teacher’s Guide Nanotechnology Reading.docx68.57 KB
File Lesson1.1bv1- Nanotech Reading.docx69 KB
File Lesson1.1bv2 NanotechnologyReading.docx159.33 KB
File Lesson1.1bv2-NanoReading Review.docx50.47 KB
File Lesson1.2 a- Nano Scale Walk.docx137.49 KB
File Lesson1.2b- That's Huge.docx63.19 KB
File Lesson1.2b-TeachersGuide That's Huge.docx121.91 KB
File Lesson1.3a M1 Assessment- Size and Scale.docx42.44 KB
File Lesson1.3b M1 Assessment- Teacher's Guide.docx122.79 KB
File Lesson2.1- Origami Surface Area.docx170.04 KB
File Lesson2.1- Student Cube Nets.pptx117.67 KB
File Lesson2.1- Teacher’s Guide Origami Surface Area.docx110.21 KB
File Lesson2.2a Flour and Fire .docx123.38 KB
File Lesson2.2a- Teacher’s Guide Flour and Fire.docx99.79 KB
File Lesson2.2b- Potato Reactions.docx98.93 KB
File Lesson2.2b- Teacher’s Guide Potato Reactions.docx1.34 MB
File Lesson2.2c- Teacher’s Guide AlkaSeltzer Inquiry Lab.docx97.9 KB
File Lesson2.2c-AlkaSeltzer Inquiry Lab.docx107.16 KB
File Lesson2.3a- Teacher’s Guide Sticker Origami.docx449.95 KB
File Lesson2.3a-StickerOrigami.docx98.15 KB
File Lesson2.3b- Teacher’s Guide Nano or Normal.docx117.06 KB
File Lesson2.3b-Nano or Normal.docx107.11 KB
File Lesson2.4a M2 Assessment-TeachersGuide.docx106.09 KB
File Lesson2.4b M2Assesment- How do Nanoparticles Work?.docx44.44 KB
File Lesson3.1- Surface Area Reading.docx775.76 KB
File Lesson3.1- Teacher'sGuide and Key Surface Area Reading.docx710.67 KB
File Lesson3.2- NanoParticleApplication.pptx11.01 MB
File Lesson3.2- Student Note Sheet Nanoparticle Application.docx74.55 KB
File Lesson3.2- Teacher Presentation Notes.docx105.41 KB
File Lesson3.3a M3 Assessment-TeachersGuide.docx97.05 KB
File Lesson3.3b M3Assessment- NanotechnologyReview.docx111.02 KB
File Lesson3.4a FinalBuild A Particle- Student.docx1.05 MB
File Lesson3.4b FinalProject BuildAParticle-TeachersGuide.docx917.11 KB
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