Safinya Group Publications by Subject

Safinya Group Publications by Year

Books and Book Chapters - Cytoskeleton - CL-NA Complexes - Microchannels - X-Ray Methods - XSFA
Lamellar Hydrogels from PEG-Lipids - Bacteriorhodopsin - Liquid Crystals - Lipid Membranes - Others

Also check out our Research Highlights & Selected Papers !

   

Books and Book Chapters

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  Lipid-DNA Interactions: Structure-Function Studies of Nanomaterials for Gene Delivery: Ewert, K. K.; Samuel, C. E. and Safinya, C. R. in Interaction of DNA with Surfactant and Polymers, pp. 377-404; Eds.: R. Dias, B. Lindman; Blackwell, Boston, MA, 2008.
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  Non-Viral Gene Delivery with Cationic Liposome-DNA Complexes: Ewert, K. K.; Ahmad, A.; Bouxsein, N. F.; Evans, H. M. and Safinya, C. R. in Gene Therapy Protocols (3rd Ed.); Ed.: J. Le Doux; Humana Press, Totowa, NJ, 2008.
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    Inspired by Biology: From Molecules to Materials to Machines. National Research Council of the National Academies, Committee Report on Biomolecular Materials and Processes; National Academy Press, Washington, D. C., 2008; ISBN 978-0-309-11704-3.    
    Biophysics and Biomolecular Materials: Safinya, C. R. in New Physics for the Twenty-first Century; Ed.: G. Fraser; Cambridge University Press, Cambridge and New York, 2006; ISBN 0-521-81600-9.    
    International Evaluation of Swedish Condensed Matter Physics, 2004. Vetenskapsrådets Rapportserie 12:2005; Swedish Research Council Publication, 2005; ISBN 91-7307-073-4. (available on line and also at www.vr.se/publikationer);  
  Lipoplex Structures and their Distinct Cellular Pathways: Ewert, K.; Evans, H. M.; Ahmad, A.; Slack, N. L.; Lin, A. J.; Martin-Herranz, A. and Safinya, C. R. in Non-viral Vectors for Gene Therapy (2nd Ed., Part I: Advances in Genetics, vol. 53), pp.117-153; Eds.: L. Huang, M.-C. Hung, E. Wagner; Elsevier, London, 2005.
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    Supramolecular Assembly in Biological Molecules: Safinya, C. R. in Forces, Growth and Form in Soft Condensed Matter: At the Interface between Physics and Biology; Eds.: A. Skjeltorp, A. V. Belushkin; Kluwer Academic Pubs., Netherlands, 2004.    
  Structure and structure-activity correlations of cationic lipid/DNA complexes: supramolecular assembly and gene delivery: Safinya, C. R.; Lin, A. J.; Slack, N. E. and Koltover, I. in Pharmaceutical Perspectives of Nucleic Acid-Based Therapeutics; Eds.: R. I. Mahato, S. W. Kim; Taylor & Francis, London & New York, 2002.    
    Cooperative Stewardship: Managing the Nation’s Multidisciplinary User Facilities for Research with Synchrotron Radiation, Neutrons, and High Magnetic Fields. National Research Council of the National Academies, Committee Report; National Academy Press, Washington, D. C., 1999; ISBN 0-309-06831-2.    
  Self Assembled Structures of Lipid-DNA Nonviral Gene Delivery Systems from Synchrotron X-Ray Diffraction: Safinya, C. R. and Koltover, I. in Non-Viral Vectors for Gene Therapy; Eds.: L. Huang, M.-C. Hung, E. Wagner; Academic Press, San Diego, 1999.
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  Imaging Complex Fluids under Confinement and Flow: Development of Bragg-Fresnel Optics for X-Ray Microdiffraction: Li, Y.; Idziak, S. H. J.; Caine, E.; Subramanian, G.; Hu, E.; Safinya, C. R. in Dynamics in Small Confining Systems III, pp. 301-306; Eds.: J. M. Drake, J. Klafter, R. Kopelman; Materials Research Society, Pittsburgh, 1997.    
    Membrane-Associated-Proteins: Self-Assembly, Interactions, and Biomolecular Materials: Safinya, C. R. and Shen, Y. in Physics of Biomaterials: Fluctuations, Self-Assembly, and Evolution, pp. 103-134; Eds.: T. Riste, D. Sherrington; Kluwer Academic, Amsterdam, 1996.
   
  The Application of the X-ray Surface Forces Apparatus (XSFA) to studies of Confined Complex Fluid Systems: Koltover, I.; Idziak, S. H. J.; Safinya, C. R.; Steinberg, S.; Israelachvili, J. N.; Liang, K. S. in Dynamics in Small Confining Systems, pp. 101-105; Eds.: J. M. Drake, J. Klafter, S. M. Troian, R. Kopelman; Materials Research Society, Pittsburgh, 1995.    
  Lyotropic Lamellar Lα Phases: Roux, D.; Safinya, C. R. and Nallet, F. in Micelles, Membranes, Microemulsions and Monolayers, pp. 303-338; Eds.: A. Ben-Shaul, W. M. Gelbart, D. Roux; Springer, New York, 1994.
   
  The Structure of Complex Fluids under Flow and Confinement: Idziak, S. H. J.; Safinya, C. R.; Liang, K. S.; Israelachvili, J. N. in Structure and Flow in Surfactant Solutions; Eds.: C. A. Herb, R. K. Prud'homme; American Chemical Society, Cleveland, 1994.    
  A New Mechanism for Lubrication in Liquid Crystals: Bruinsma, R. F.; Safinya, C. R. in Dynamics in Small Confining Systems, pp. 3-9; Eds.: J. M. Drake, J. Klafter, D. D. Awshalom, R. Kopelman; Materials Research Society, Pittsburgh, 1993.    
  Macromolecular Liquids. Eds. C. R. Safinya, S. A. Safran, P. A. Pincus; Materials Research Society Publishers, Pittsburgh, PA, 1989 (Vol. 177).    
  Rigid and Fluctuating Surfaces: A Series of Synchrotron X-ray Scattering Studies of Interacting Stacked Membranes: Safinya, C. R. in Phase Transitions in Soft Condensed Matter; Eds.: T. Riste, D. Sherrington; Plenum Press, New York and London, 1989.    
   

Cytoskeleton

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  Hesse, H. C.; Beck, R.; Ding, C.; Jones, J. B.; Deek, J.; MacDonald, N. C.; Li, Y.; Safinya, C. R.: Direct Imaging of Aligned Neurofilament Networks Assembled Using In Situ Dialysis in Microchannels. Langmuir 2008, 24, 8397-8401 (cover of Aug 19 issue).  
    Jones, J. B.; Safinya, C. R., Interplay between Liquid Crystalline and Isotropic Gels in Self-Assembled Neurofilament Networks. Biophys. J. 2008, 95, 823-825.  
    Ikawa, T.; Hoshino, F.; Watanabe, O.; Li, Y. L.; Pincus, P.; Safinya, C. R.: Molecular scale imaging of F-actin assemblies immobilized on a photopolymer surface. Phys. Rev. Lett. 2007, 98, 018101.  
    Raviv, U.; Needleman, D. J.; Ewert, K. K.; Safinya, C. R., Hierarchical bionanotubes formed by the self assembly of microtubules with cationic membranes or polypeptides. Journal of Applied Crystallography 2007, 40, S83-S87. PDF icon  
    Raviv, U.; Nguyen, T.; Ghafouri, R.; Needleman, D. J.; Li, Y. L.; Miller, H. P.; Wilson, L.; Bruinsma, R. F.; Safinya, C. R.: Microtubule protofilament number is modulated in a stepwise fashion by the charge density of an enveloping layer. Biophys. J. 2007, 92, 278-287 (cover of Jan 1 issue).  
    Raviv, U.; Needleman, D. J.; Safinya, C. R.: Cationic membranes complexed with oppositely charged microtubules: hierarchical self-assembly leading to bio-nanotubes. J. Phys.: Condens. Matter 2006, 18, S1271-S1279.  
    Hirst, L. S.; Pynn, R.; Bruinsma, R. F.; Safinya, C. R.: Hierarchical self-assembly of actin bundle networks: Gels with surface protein skin layers. J. Chem. Phys. 2005, 123, 104902.  
    Needleman, D. J.; Jones, J. B.; Raviv, U.; Ojeda-Lopez, M. A.; Miller, H. P.; Li, Y.; Wilson, L.; Safinya, C. R.: Supramolecular assembly of biological molecules purified from bovine nerve cells: from microtubule bundles and necklaces to neurofilament networks. J. Phys.: Condens. Matter 2005, 17, S3225-S3230.
 
    Needleman, D. J.; Ojeda-Lopez, M. A.; Raviv, U.; Ewert, K.; Miller, H. P.; Wilson, L.; Safinya, C. R.: Radial compression of microtubules and the mechanism of action of taxol and associated proteins. Biophys. J. 2005, 89, 3410-3423.
 
    Raviv, U.; Needleman, D. J.; Li, Y. L.; Miller, H. P.; Wilson, L.; Safinya, C. R.: Cationic liposome-microtubule complexes: Pathways to the formation of two-state lipid-protein nanotubes with open or closed ends. Proc. Natl. Acad. Sci. U.S.A. 2005, 102, 11167-11172.
 
    Needleman, D. J.; Ojeda-Lopez, M. A.; Raviv, U.; Miller, H. P.; Wilson, L.; Safinya, C. R.: Higher-order assembly of microtubules by counterions: From hexagonal bundles to living necklaces. Proc. Natl. Acad. Sci. U.S.A. 2004, 101, 16099-16103 (featured on the cover of the Nov 16 issue).
 
    Needleman, D. J.; Ojeda-Lopez, M. A.; Raviv, U.; Ewert, K.; Jones, J. B.; Miller, H. P.; Wilson, L.; Safinya, C. R.: Synchrotron X-ray diffraction study of microtubules buckling and bundling under osmotic stress: A probe of interprotofilament interactions. Phys. Rev. Lett. 2004, 93, 198104.
 
    Hirst, L. S.; Safinya, C. R.: Skin layer at the actin-gel surface: Quenched protein membranes form flat, crumpled, and tubular morphologies. Phys. Rev. Lett. 2004, 93, 018101.
 
  Bouxsein, N. F.; Hirst, L. S.; Li, Y. L.; Safinya, C. R.; Abu Samah, Z.; MacDonald, N. C.; Pynn, R.: Alignment of filamentous proteins and associated molecules through confinement in microchannels. Appl. Phys. Lett. 2004, 85, 5775-5777.  
    Pelletier, O.; Pokidysheva, E.; Hirst, L. S.; Bouxsein, N.; Li, Y.; Safinya, C. R.: Structure of actin cross-linked with alpha-actinin: A network of bundles. Phys. Rev. Lett. 2003, 91, 148102 (cover of Oct 3 issue).
 
  Wong, G. C. L.; Lin, A.; Tang, J. X.; Li, Y.; Janmey, P. A.; Safinya, C. R.: Lamellar phase of stacked two-dimensional rafts of actin filaments. Phys. Rev. Lett. 2003, 91.
 
    Wong, G. C. L.; Tang, J. X.; Lin, A.; Li, Y. L.; Janmey, P. A.; Safinya, C. R.: Hierarchical self-assembly of F-actin and cationic lipid complexes: Stacked three-layer tubule networks. Science 2000, 288, 2035-2039.
 
   

Cationic Lipid–Nucleic Acid Complexes

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Lipid Membranes   Zidovska, A.; Ewert, K. K.; Quispe, J.; Carragher, B.; Potter, C. S.; Safinya, C. R.: The effect of salt and pH on block liposomes studied by cryogenic transmission electron microscopy. Biochim. Biophys. Acta - Biomembranes 2009, xxx, xxx-xxx.  
    Zidovska, A.; Evans, H. M.; Ewert, K. K.; Quispe, J.; Carragher, B.; Potter, C. S.; Safinya, C. R.: Liquid Crystalline Phases of Dendritic Lipid–DNA Self-Assemblies: Lamellar, Hexagonal and DNA Bundles. J. Phys. Chem. B 2009, 113, 3694-3703 (invited issue in memory of P. G. De Gennes).  
  Zidovska, A.; Ewert, K. K.; Quispe, J.; Carragher, B.; Potter, C. S.; Safinya, C. R., Block Liposomes from Curvature-Stabilizing Lipids: Connected Nanotubes, –rods or –spheres. Langmuir 2009, 25, 2979-2985 (cover of Mar 3 issue).  
    Zidovska, A.; Evans, H. M.; Ahmad, A.; Ewert, K. K.; Safinya, C. R.: The Role of Cholesterol and Structurally Related Molecules in Enhancing Transfection by Cationic Liposome–DNA Complexes. J. Phys. Chem. 2009, 113, 5208-5216 (cover of Apr 16 issue).  
    Farago, O.; Ewert, K. K.; Ahmad, A.; Evans, H. M.; Grønbech-Jensen, N.; Safinya, C. R.: Transitions between Distinct Compaction Regimes in Complexes of Multivalent Cationic Lipids and DNA. Biophys. J. 2008, 93, 836-846.  
  Lipid-DNA Interactions: Structure-Function Studies of Nanomaterials for Gene Delivery: Ewert, K. K.; Samuel, C. E. and Safinya, C. R. in Interaction of DNA with Surfactant and Polymers, pp. 377-404; Eds.: R. Dias, B. Lindman; Blackwell, Boston, MA, 2008.
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  Non-Viral Gene Delivery with Cationic Liposome-DNA Complexes: Ewert, K. K.; Ahmad, A.; Bouxsein, N. F.; Evans, H. M. and Safinya, C. R. in Gene Therapy Protocols (3rd Ed.); Ed.: J. Le Doux; Humana Press, Totowa, NJ, 2008.
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    Bouxsein, N. F.; McAllister, C. S.; Ewert, K. K.; Samuel, C. E.; Safinya, C. R., Structure and gene silencing activities of monovalent and pentavalent cationic lipid vectors complexed with siRNA. Biochemistry 2007, 46, 4785-4792.  
    Safinya, C. R.; Ewert, K.; Ahmad, A.; Evans, H. M.; Raviv, U.; Needleman, D. J.; Lin, A. J.; Slack, N. L.; George, C.; Samuel, C. E.: Cationic liposome-DNA complexes: from liquid crystal science to gene delivery applications. Philosoph. Trans. R. Soc. London, Ser. A 2006, 364, 2573-2596.
 
    Ewert, K. K.; Evans, H. M.; Zidovska, A.; Bouxsein, N. F.; Ahmad, A.; Safinya, C. R.: A columnar phase of dendritic lipid-based cationic liposome-DNA complexes for gene delivery: Hexagonally ordered cylindrical micelles embedded in a DNA honeycomb lattice. J. Am. Chem. Soc. 2006, 128, 3998-4006.
 
    Ewert, K. K.; Evans, H. M.; Bouxsein, N. F.; Safinya, C. R.: Dendritic cationic lipids with highly charged headgroups for efficient gene delivery. Bioconjugate Chem. 2006, 17, 877-888.  
    Ahmad, A.; Evans, H. M.; Ewert, K.; George, C. X.; Samuel, C. E.; Safinya, C. R.: New multivalent cationic lipids reveal bell curve for transfection efficiency versus membrane charge density: lipid-DNA complexes for gene delivery. J. Gene Med. 2005, 7, 739-748.
 
    Ewert, K. K.; Ahmad, A.; Evans, H. M.; Safinya, C. R.: Cationic lipid-DNA complexes for non-viral gene therapy: relating supramolecular structures to cellular pathways. Expert Opin. Biol. Ther. 2005, 5, 33-53.
 
  Lipoplex Structures and their Distinct Cellular Pathways: Ewert, K.; Evans, H. M.; Ahmad, A.; Slack, N. L.; Lin, A. J.; Martin-Herranz, A. and Safinya, C. R. in Non-viral Vectors for Gene Therapy (2nd Ed., Part I: Advances in Genetics, vol. 53), pp.117-153; Eds.: L. Huang, M.-C. Hung, E. Wagner; Elsevier, London, 2005.
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    Ewert, K.; Slack, N. L.; Ahmad, A.; Evans, H. M.; Lin, A. J.; Samuel, C. E.; Safinya, C. R.: Cationic lipid-DNA complexes for gene therapy: Understanding the relationship between complex structure and gene delivery pathways at the molecular level. Curr. Med. Chem. 2004, 11, 133-149 (cover of Jan issue).
 
    Safinya, C. R.: Non-viral vectors for gene therapy and drug delivery - Preface. Curr. Med. Chem. 2004, 11.
 
    Martin-Herranz, A.; Ahmad, A.; Evans, H. M.; Ewert, K.; Schulze, U.; Safinya, C. R.: Surface functionalized cationic lipid-DNA complexes for gene delivery: PEGylated lamellar complexes exhibit distinct DNA-DNA interaction regimes. Biophys. J. 2004, 86, 1160-1168.  
    Lin, A. J.; Slack, N. L.; Ahmad, A.; George, C. X.; Samuel, C. E.; Safinya, C. R.: Three-dimensional imaging of lipid gene-carriers: Membrane charge density controls universal transfection behavior in lamellar cationic liposome-DNA complexes. Biophys. J. 2003, 84, 3307-3316.
 
    Evans, H. M.; Ahmad, A.; Ewert, K.; Pfohl, T.; Martin-Herranz, A.; Bruinsma, R. F.; Safinya, C. R.: Structural polymorphism of DNA-dendrimer complexes. Phys. Rev. Lett. 2003, 91.
 
    Ewert, K.; Ahmad, A.; Evans, H. M.; Schmidt, H. W.; Safinya, C. R.: Efficient synthesis and cell-transfection properties of a new multivalent cationic lipid for nonviral gene delivery. J. Med. Chem. 2002, 45, 5023-5029.
 
  Structure and structure-activity correlations of cationic lipid/DNA complexes: supramolecular assembly and gene delivery: Safinya, C. R.; Lin, A. J.; Slack, N. E. and Koltover, I. in Pharmaceutical Perspectives of Nucleic Acid-Based Therapeutics; Eds.: R. I. Mahato, S. W. Kim; Taylor & Francis, London & New York, 2002.    
    Safinya, C. R.: Structures of lipid-DNA complexes: supramolecular assembly and gene delivery. Curr. Opin. Struct. Biol. 2001, 11, 440-448.  
    Koltover, I.; Wagner, K.; Safinya, C. R.: DNA condensation in two dimensions. Proc. Natl. Acad. Sci. U.S.A. 2000, 97, 14046-14051.
 
    Lin, A. J.; Slack, N. L.; Ahmad, A.; Koltover, I.; George, C. X.; Samuel, C. E.; Safinya, C. R.: Structure and structure-function studies of lipid/plasmid DNA complexes. J. Drug Targeting 2000, 8, 13-27. link to article  
    Schulze, U.; Schmidt, H. W.; Safinya, C. R.: Synthesis of novel cationic poly(ethylene glycol) containing lipids. Bioconjugate Chem. 1999, 10, 548-552.
 
    Koltover, I.; Salditt, T.; Safinya, C. R.: Phase diagram, stability, and overcharging of lamellar cationic lipid-DNA self-assembled complexes. Biophys. J. 1999, 77, 915-924.
 
  Self Assembled Structures of Lipid-DNA Nonviral Gene Delivery Systems from Synchrotron X-Ray Diffraction: Safinya, C. R. and Koltover, I. in Non-Viral Vectors for Gene Therapy; Eds.: L. Huang, M.-C. Hung, E. Wagner; Academic Press, San Diego, 1999.
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  Wong, G. C. L.; Li, Y. L.; Koltover, I.; Safinya, C. R.; Cai, Z. H.; Yun, W. B.: Mesoscopic structure of DNA-membrane self-assemblies: Microdiffraction and manipulation on lithographic substrates. Appl. Phys. Lett. 1998, 73, 2042-2044.
 
    Rädler, J. O.; Koltover, I.; Jamieson, A.; Salditt, T.; Safinya, C. R.: Structure and interfacial aspects of self-assembled cationic lipid-DNA gene carrier complexes. Langmuir 1998, 14, 4272-4283.
 
    Koltover, I.; Salditt, T.; Rädler, J. O.; Safinya, C. R.: An inverted hexagonal phase of cationic liposome-DNA complexes related to DNA release and delivery. Science 1998, 281, 78-81.
 
  Li, Y.; Wong, G. C. L.; Caine, E.; Hu, E. L.; Safinya, C. R.: Structural studies of DNA cationic lipid complexes confined in lithographically patterned microchannel arrays. Int. J. Thermophys. 1998, 19, 1165-1174.
 
    Salditt, T.; Koltover, I.; Rädler, J. O.; Safinya, C. R.: Self-assembled DNA-cationic-lipid complexes: Two-dimensional smectic ordering, correlations, and interactions. Phys. Rev. E 1998, 58, 889-904.
 
    Safinya, C. R.; Koltover, I.; Rädler, J.: DNA at membrane surfaces: an experimental overview. Curr. Opin. Colloid Interf. Sci. 1998, 3, 69-77.
 
  Salditt, T.; Koltover, I.; Rädler, J. O.; Safinya, C. R.: Two-dimensional smectic ordering of linear DNA chains in self-assembled DNA-cationic liposome mixtures. Phys. Rev. Lett. 1997, 79, 2582-2585.
 
    Rädler, J. O.; Koltover, I.; Salditt, T.; Safinya, C. R.: Structure of DNA-cationic liposome complexes: DNA intercalation in multilamellar membranes in distinct interhelical packing regimes. Science 1997, 275, 810-814.
 
   

Microchannels

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  Hesse, H. C.; Beck, R.; Ding, C.; Jones, J. B.; Deek, J.; MacDonald, N. C.; Li, Y.; Safinya, C. R.: Direct Imaging of Aligned Neurofilament Networks Assembled Using In Situ Dialysis in Microchannels. Langmuir 2008, 24, 8397-8401 (cover of Aug 19 issue).  
    Zuruzi, A. S.; Butler, B. C.; MacDonald, N. C.; Safinya, C. R.: Nanostructured TiO2 thin films as porous cellular interfaces. Nanotechnol. 2006, 17, 531-535.  
    Choi, M. C.; Santangelo, C. D.; Pelletier, O.; Kim, J. H.; Kwon, S. Y.; Wen, Z.; Li, Y.; Pincus, P. A.; Safinya, C. R.; Kim, M. W.: Direct observation of biaxial confinement of a semiflexible filament in a channel. Macromolecules 2005, 38, 9882-9884.
 
    Hirst, L. S.; Parker, E. R.; Abu-Samah, Z.; Li, Y.; Pynn, R.; MacDonald, N. C.; Safinya, C. R.: Microchannel systems in titanium and silicon for structural and mechanical studies of aligned protein self-assemblies. Langmuir 2005, 21, 3910-3914.  
    Choi, M. C.; Pfohl, T.; Wen, Z. Y.; Li, Y. L.; Kim, M. W.; Israelachvili, J. N.; Safinya, C. R.: Ordered patterns of liquid crystal toroidal defects by microchannel confinement. Proc. Natl. Acad. Sci. U.S.A. 2004, 101, 17340-17344 (featured on the cover of the Dec 14 issue).
 
  Bouxsein, N. F.; Hirst, L. S.; Li, Y. L.; Safinya, C. R.; Abu Samah, Z.; MacDonald, N. C.; Pynn, R.: Alignment of filamentous proteins and associated molecules through confinement in microchannels. Appl. Phys. Lett. 2004, 85, 5775-5777.  
    Pfohl, T.; Li, Y.; Kim, J. H.; Wen, Z.; Wong, G. C. L.; Koltover, I.; Kim, M. W.; Safinya, C. R.: Biological polyelectrolyte complexes in solution and confined on patterned surfaces. Colloids and Surfaces A-Physicochemical and Engineering Aspects 2002, 198, 613-623.  
    Li, Y.; Pfohl, T.; Kim, J. H.; Yasa, M.; Wen, Z.; Kim, M. W.; Safinya C. R.: Selective Surface Modification in Silicon Micro-fluidic Channels for Micro-manipulation of Biological Macromolecules. Biomed. Microdevices 2001, 3, 239-244.    
    Pfohl, T.; Kim, J. H.; Yasa, M.; Miller, H. P.; Wong, G. C. L.; Bringezu, F.; Wen, Z.; Wilson, L.; Kim, M. W.; Li, Y.; Safinya, C. R.: Controlled modification of microstructured silicon surfaces for confinement of biological macromolecules and liquid crystals. Langmuir 2001, 17, 5343-5351.
 
  Wong, G. C. L.; Li, Y. L.; Koltover, I.; Safinya, C. R.; Cai, Z. H.; Yun, W. B.: Mesoscopic structure of DNA-membrane self-assemblies: Microdiffraction and manipulation on lithographic substrates. Appl. Phys. Lett. 1998, 73, 2042-2044.
 
  Li, Y.; Wong, G. C. L.; Caine, E.; Hu, E. L.; Safinya, C. R.: Structural studies of DNA cationic lipid complexes confined in lithographically patterned microchannel arrays. Int. J. Thermophys. 1998, 19, 1165-1174.
 
   

X-Ray Methods

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    Li, Y. L.; Yasa, M.; Pelletier, O.; Safinya, C. R.; Caine, E.; Hu, E. E.; Fernandez, P.: Metal layer Bragg-Fresnel lenses for diffraction focusing of hard x-rays. Appl. Phys. Lett. 2003, 82, 2538-2540.  
    Li, Y.; Wong, G. C. L.; Case, R.; Safinya, C. R.; Caine, E.; Hu, E.; Fernandez, P.: Characterizing the hard x-ray diffraction properties of a GaAs linear Bragg-Fresnel lens. Appl. Phys. Lett. 2000, 77, 313-315.
 
    Li, Y. L.; Wong, G. C. L.; Safinya, C. R.; Caine, E.; Hu, E. L.; Haeffner, D.; Fernandez, P.; Yun, W. B.: Bragg-Fresnel optics for hard x-ray microscopy: Development of fabrication process and x-ray characterization at the Advanced Photon Source. Rev. Sci. Instrum. 1998, 69, 2844-2848.  
    Caine, E. J.; Shi, S.; Hu, E. L.; Li, Y.; Idziak, S. H. J.; Subramanian, G.; Safinya, C. R.: Fabrication and characterization of III-V compound semiconductor Bragg-Fresnel lenses for hard X-ray microfocusing. Microelectron. Eng. 1997, 35, 289-292.
 
  Imaging Complex Fluids under Confinement and Flow: Development of Bragg-Fresnel Optics for X-Ray Microdiffraction: Li, Y.; Idziak, S. H. J.; Caine, E.; Subramanian, G.; Hu, E.; Safinya, C. R. in Dynamics in Small Confining Systems III, pp. 301-306; Eds.: J. M. Drake, J. Klafter, R. Kopelman; Materials Research Society, Pittsburgh, 1997.    
    Plano, R. J.; Safinya, C. R.; Sirota, E. B.; Wenzel, L. J.: X-Ray Couette Shear Cell for Nonequilibrium Structural Studies of Complex Fluids under Flow. Rev. Sci. Instrum. 1993, 64, 1309-1318.
 
  Sirota, E. B.; Smith, G. S.; Safinya, C. R.; Plano, R. J.; Clark, N. A., X-ray Scattering Studies of Aligned Stacked Surfactant Membranes. Science 1988, 242, 1406-1409.  
  Smith, G. S.; Safinya, C. R.; Roux, D.; Clark, N. A., X-ray Study of Freely Suspended Films of a Multilamellar Lipid System. Mol. Cryst. Liq. Cryst. 1987, 144, 235-255.    
   

XSFA (X-Ray Surface Forces Apparatus)

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    Gourdon, D.; Yasa, M.; Alig, A. R. G.; Li, Y. L.; Safinya, C. R.; Israelachvili, J. N.: Mechanical and structural properties of BaCrO4 nanorod films under confinement and shear. Adv. Funct. Mater. 2004, 14, 238-242.
 
    Golan, Y.; Seitz, M.; Luo, C.; Martin-Herranz, A.; Yasa, M.; Li, Y. L.; Safinya, C. R.; Israelachvili, J.: The x-ray surface forces apparatus for simultaneous x-ray diffraction and direct normal and lateral force measurements. Rev. Sci. Instrum. 2002, 73, 2486-2488.
 
    Li, Y.; Golan, Y.; Martin-Herranz, A.; Pelletier, O.; Yasa, M.; Israelachivili, J. N.; Safinya, C. R.: In situ X-ray diffraction studies of a multilayered membrane fluid under confinement and shear. Int. J. Thermophys. 2001, 22, 1175-1184.
 
    Golan, Y.; Martin-Herranz, A.; Li, Y.; Safinya, C. R.; Israelachvili, J.: Direct observation of shear-induced orientational phase coexistence in a lyotropic system using a modified X-ray surface forces apparatus. Phys. Rev. Lett. 2001, 86, 1263-1266.
 
    Koltover, I.; Idziak, S. H. J.; Davidson, P.; Li, Y.; Safinya, C. R.; Ruths, M.; Steinberg, S.; Israelachvili, J. N.: Alignment of complex fluids under confinement and flow. J. Phys. II 1996, 6, 893-907.
 
    Idziak, S. H. J.; Koltover, I.; Israelachvili, J. N.; Safinya, C. R.: Structure in a confined smectic liquid crystal with competing surface and sample elasticities. Phys. Rev. Lett. 1996, 76, 1477-1480.
 
    Idziak, S. H. J.; Koltover, I.; Davidson, P.; Ruths, M.; Li, Y. L.; Israelachvili, J. N.; Safinya, C. R.: Structure under confinement in a smectic - A and lyotropic surfactant hexagonal phase. Physica B 1996, 221, 289-295.  
  The Application of the X-ray Surface Forces Apparatus (XSFA) to studies of Confined Complex Fluid Systems: Koltover, I.; Idziak, S. H. J.; Safinya, C. R.; Steinberg, S.; Israelachvili, J. N.; Liang, K. S. in Dynamics in Small Confining Systems, pp. 101-105; Eds.: J. M. Drake, J. Klafter, S. M. Troian, R. Kopelman; Materials Research Society, Pittsburgh, 1995.    
    Idziak, S. H. J.; Koltover, I.; Liang, K. S.; Israelachvili, J. N.; Safinya, C. R.: Study of Flow in a Smectic Liquid-Crystal in the X-Ray Surface Forces Apparatus. Int. J. Thermophys. 1995, 16, 299-307.
 
  Idziak, S. H. J.; Safinya, C. R.; Hill, R. S.; Kraiser, K. E.; Ruths, M.; Warriner, H. E.; Steinberg, S.; Liang, K. S.; Israelachvili, J. N.: The X-Ray Surface Forces Apparatus - Structure of a Thin Smectic Liquid-Crystal Film under Confinement. Science 1994, 264, 1915-1918.
 
  The Structure of Complex Fluids under Flow and Confinement: Idziak, S. H. J.; Safinya, C. R.; Liang, K. S.; Israelachvili, J. N. in Structure and Flow in Surfactant Solutions; Eds.: C. A. Herb, R. K. Prud'homme; American Chemical Society, Cleveland, 1994.    
   

Lamellar Hydrogels from PEG-Lipids

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    Slack, N. L.; Davidson, P.; Chibbaro, M. A.; Jeppesen, C.; Eiselt, P.; Warriner, H. E.; Schmidt, H. W.; Pincus, P.; Safinya, C. R.: The bridging conformations of double-end anchored polymer-surfactants destabilize a hydrogel of lipid membranes. J. Chem. Phys. 2001, 115, 6252-6257.
 
    Warriner, H. E.; Keller, S. L.; Idziak, S. H. J.; Slack, N. L.; Davidson, P.; Zasadzinski, J. A.; Safinya, C. R.: The influence of polymer molecular weight in lamellar gels based on PEG-lipids. Biophys. J. 1998, 75, 272-293.
 
    Slack, N. L.; Schellhorn, M.; Eiselt, P.; Chibbaro, M. A.; Schulze, U.; Warriner, H. E.; Davidson, P.; Schmidt, H. W.; Safinya, C. R.: Synthesis and phase behavior of new amphiphilic PEG-based triblock copolymers as gelling agents for lamellar liquid crystalline phases. Macromolecules 1998, 31, 8503-8508.
 
    Warriner, H. E.; Davidson, P.; Slack, N. L.; Schellhorn, M.; Eiselt, P.; Idziak, S. H. J.; Schmidt, H. W.; Safinya, C. R.: Lamellar biogels comprising fluid membranes with a newly synthesized class of polyethylene glycol-surfactants. J. Chem. Phys. 1997, 107, 3707-3722.
 
  Keller, S. L.; Warriner, H. E.; Safinya, C. R.; Zasadzinski, J. A.: Direct observation of a defect-mediated viscoelastic transition in a hydrogel of lipid membranes and polymer lipids. Phys. Rev. Lett. 1997, 78, 4781-4784.
 
    Warriner, H. E.; Idziak, S. H. J.; Slack, N. L.; Davidson, P.; Safinya, C. R.: Lamellar biogels: Fluid-membrane-based hydrogels containing polymer lipids. Science 1996, 271, 969-973.
 
   

Bacteriorhodopsin

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    Koltover, I.; Raedler, J. O.; Salditt, T.; Rothschild, K. J.; Safinya, C. R.: Phase behavior and interactions of the membrane-protein bacteriorhodopsin. Phys. Rev. Lett. 1999, 82, 3184-3187.  
  Koltover, I.; Salditt, T.; Rigaud, J. L.; Safinya, C. R.: Stacked 2D crystalline sheets of the membrane-protein bacteriorhodopsin: A specular and diffuse reflectivity study. Phys. Rev. Lett. 1998, 81, 2494-2497.
 
    Shen, Y.; Safinya, C. R.; Liang, K. S.; Ruppert, A. F.; Rothschild, K. J.: Stabilization of the Membrane-Protein Bacteriorhodopsin to 140-Degrees-C in 2-Dimensional Films. Nature 1993, 366, 48-50.
 
   

Liquid Crystals

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    Lei, N.; Safinya, C. R.; Roux, D.; Liang, K. S.: Synchrotron x-ray-scattering studies on the sodium dodecyl sulfate-water-pentanol-dodecane L-3 sponge phase. Phys. Rev. E 1997, 56, 608-613.
 
  Lyotropic Lamellar Lα Phases: Roux, D.; Safinya, C. R. and Nallet, F. in Micelles, Membranes, Microemulsions and Monolayers, pp. 303-338; Eds.: A. Ben-Shaul, W. M. Gelbart, D. Roux; Springer, New York, 1994.
   
    Safinya, C. R.; Sirota, E. B.; Bruinsma, R. F.; Jeppesen, C.; Plano, R. J.; Wenzel, L. J.: Structure of Membrane Surfactant and Liquid-Crystalline Smectic Lamellar Phases under Flow. Science 1993, 261, 588-591.
 
  A New Mechanism for Lubrication in Liquid Crystals: Bruinsma, R. F.; Safinya, C. R. in Dynamics in Small Confining Systems, pp. 3-9; Eds.: J. M. Drake, J. Klafter, D. D. Awshalom, R. Kopelman; Materials Research Society, Pittsburgh, 1993.    
    Willis, P. C.; Clark, N. A.; Xue, J. Z.; Safinya, C. R.: Local Layer Structure of the Steep Field Line Defect in Surface-Stabilized Ferroelectric Liquid-Crystal Cells. Liq. Cryst. 1992, 12, 891-904.
   
    Willis, P. C.; Clark, N. A.; Safinya, C. R.: Molecular Director and Layer Response of Chevron Surface Stabilized Ferroelectric Liquid-Crystals to Low Electric-Field. Liq. Cryst. 1992, 11, 581-592.    
    Safinya, C. R.; Sirota, E. B.; Plano, R. J., The Nematic to Smectic-A Transition under Shear Flow: A Nonequilibrium Synchrotron X-ray Study. Phys. Rev. Lett. 1991, 66, 1986-1989.  
    Bruinsma, R. F.; Safinya, C. R., Landau Theory of the Nematic to Smectic-A Phase Transition Under Shear Flow. Phys. Rev. A 1991, 43, 5377-5404.  
  Roux, D.; Safinya, C. R., A Synchrotron X-ray study of Competing Undulation and Electrostatic Interlayer Interactions in Fluid Multimembrane Lyotropic Phases. J. Phys. (Paris) 1988, 49, 307-318.    
    Ocko, B. M.; Pershan, P. S.; Safinya, C. R.; Chiang, L. Y., Incommensurate Smectic Order at the Free Surface in the Nematic Phase of DB7NO2. Phys. Rev. A 1987, 35, 1868-1872.  
    Rieker, T. P.; Clark, N. A.; Smith, G. S.; Parmar, D. S.; Sirota, E. B.; Safinya, C. R., "Chevron" Local Layer Structure in Surface Stabilized Ferroelectric Smectic C Cells. Phys. Rev. Lett. 1987, 59, 2658-2661.  
    Safinya, C. R.; Varady, W. A.; Chiang, L. Y.; Dimon, P., X-ray Study of the Nematic Phase and Smectic-A1-Smectic-A(antiphase) Phase Transition in Heptylphenyl nitrobenzoyloxybenzoate (DB7NO2). Phys. Rev. Lett. 1986, 57, 432-435.  
    Safinya, C. R.; Liang, K. S.; Varady, W. A.; Clark, N. A.; Andersson, G., Synchroton X-ray Study of the Orientational Ordering D2-D1 Structural Phase Transition of Freely Suspended Discotic Strands in Triphenylene-Hexa-dodecanoate. Phys. Rev. Lett. 1984, 53, 1172-1175.  
    Garland, C. W.; Meichle, M.; Ocko, B. M.; Kortan, A. R.; Safinya, C. R.; Yu, L. J.; Litster, J. D.; Birgeneau, R. J., Critical Behavior at the Nematic-Smectic-A Transition in Butyloxygenzylidene Heptylkaniline (40.7). Phys. Rev. A 1983, 27, 3234-3240.  
    Safinya, C. R.; Martinezmiranda, L. J.; Kaplan, M.; Litster, J. D.; Birgeneau, R. J., High Resolution X-ray Scattering Study of the Nematic to Smectic-C Transitions in 8S5/7S5 Mixtures. Phys. Rev. Lett. 1983, 50, 56-59.  
    Safinya, C. R.; Birgeneau, R. J.; Litster, J. D.; Neubert, M. E., Critical Fluctuations Near a Nematic-Smectic-A-Smectic-C Multicritical Point. Phys. Rev. Lett. 1981, 47, 668-671.  
    Safinya, C. R.; Kaplan, M.; Alsnielsen, J.; Birgeneau, R. J.; Davidov, D.; Litster, J. D.; Johnson, D. L.; Neubert, M. E., High Resolution X-ray Study of A Smectic-A-Smectic-C Phase Transition. Phys. Rev. B 1980, 21, 4149-4153.  
  Alsnielsen, J.; Litster, J. D.; Birgeneau, R. J.; Kaplan, M.; Safinya, C. R.; Lindegaardandersen, A.; Mathiesen, S., Observation of Algebraic Decay of Positional Order in a Smectic Liquid Crystal. Phys. Rev. B 1980, 22, 312-320.  
    Davidov, D.; Safinya, C. R.; Kaplan, M.; Dana, S. S.; Schaetzing, R.; Birgeneau, R. J.; Litster, J. D., High-Resolution X-Ray and Light Scattering Study of Critical Behavior Associated with the Nematic-Smectic-A Transition in 4-cyano-4'-octylbiphenyl. Phys. Rev. B 1979, 19, 1657-1663.  
   

Lipid Membranes

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  Zidovska, A.; Ewert, K. K.; Quispe, J.; Carragher, B.; Potter, C. S.; Safinya, C. R.: The effect of salt and pH on block liposomes studied by cryogenic transmission electron microscopy. Biochim. Biophys. Acta - Biomembranes 2009, xxx, xxx-xxx.  
  Zidovska, A.; Ewert, K. K.; Quispe, J.; Carragher, B.; Potter, C. S.; Safinya, C. R., Block Liposomes from Curvature-Stabilizing Lipids: Connected Nanotubes, –rods or –spheres. Langmuir 2009, 25, 2979-2985 (cover of Mar 3 issue).  
    Subramanian, G.; Hjelm, R. P.; Deming, T. J.; Smith, G. S.; Li, Y.; Safinya, C. R.: Structure of complexes of cationic lipids and poly(glutamic acid) polypeptides: A pinched lamellar phase. J. Am. Chem. Soc. 2000, 122, 26-34.
 
    Koltover, I.; Radler, J. O.; Safinya, C. R.: Membrane mediated attraction and ordered aggregation of colloidal particles bound to giant phospholipid vesicles. Phys. Rev. Lett. 1999, 82, 1991-1994.
 
    Lei, N.; Safinya, C. R.; Bruinsma, R. F.: Discrete Harmonic Model for Stacked Membranes - Theory and Experiment. J. Phys. II 1995, 5, 1155-1163.    
    Chiruvolu, S.; Warriner, H. E.; Naranjo, E.; Idziak, S. H. J.; Radler, J. O.; Plano, R. J.; Zasadzinski, J. A.; Safinya, C. R.: A Phase of Liposomes with Entangled Tubular Vesicles. Science 1994, 266, 1222-1225.
 
    Schmidt, C. F.; Svoboda, K.; Lei, N.; Petsche, I. B.; Berman, L. E.; Safinya, C. R.; Grest, G. S.: Existence of a Flat Phase in Red-Cell Membrane Skeletons. Science 1993, 259, 952-954.  
    Smith, G. S.; Sirota, E. B.; Safinya, C. R.; Plano, R. J.; Clark, N. A., X-ray Structural Studies of Freely Suspended Hydrated DMPC Multimembrane Films. J. Chem. Phys. 1990, 92, 4519-4529.  
    Safinya, C. R.; Sirota, E. B.; Roux, D.; Smith, G. S., Universality in Interacting Membranes: The Effect of Cosurfactants on the interfacial Rigidity. Phys. Rev. Lett. 1989, 62, 1134-1137.  
  Rigid and Fluctuating Surfaces: A Series of Synchrotron X-ray Scattering Studies of Interacting Stacked Membranes: Safinya, C. R. in Phase Transitions in Soft Condensed Matter; Eds.: T. Riste, D. Sherrington; Plenum Press, New York and London, 1989.    
  Roux, D.; Safinya, C. R., A Synchrotron X-ray study of Competing Undulation and Electrostatic Interlayer Interactions in Fluid Multimembrane Lyotropic Phases. J. Phys. (Paris) 1988, 49, 307-318.    
  Sirota, E. B.; Smith, G. S.; Safinya, C. R.; Plano, R. J.; Clark, N. A., X-ray Scattering Studies of Aligned Stacked Surfactant Membranes. Science 1988, 242, 1406-1409.  
    Smith, G. S.; Sirota, E. B.; Safinya, C. R.; Clark, N. A., Structure of the Lß' Phase in a Hydrated Phosphatidylcholine Multimembrane. Phys. Rev. Lett. 1988, 60, 813-816.  
  Smith, G. S.; Safinya, C. R.; Roux, D.; Clark, N. A., X-ray Study of Freely Suspended Films of a Multilamellar Lipid System. Mol. Cryst. Liq. Cryst. 1987, 144, 235-255.    
    Safinya, C. R.; Roux, D.; Smith, G. S.; Sinha, S. K.; Dimon, P.; Clark, N. A.; Bellocq, A. M., Steric Interactions in a Model Membrane System: A Synchrotron X-ray Study. Phys. Rev. Lett. 1986, 57, 2718-2721.  
   

Others

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  Biophysics and Biomolecular Materials: Safinya, C. R. in New Physics for the Twenty-first Century; Ed.: G. Fraser; Cambridge University Press, Cambridge and New York, 2006.    
  Supramolecular Assembly in Biological Molecules: Safinya, C. R. in Forces, Growth and Form in Soft Condensed Matter: At the Interface between Physics and Biology; Eds.: A. Skjeltorp, A. V. Belushkin; Kluwer Academic Pubs., Netherlands, 2004.    
    Granick, S.; Kumar, S. K.; Amis, E. J.; Antonietti, M.; Balazs, A. C.; Chakraborty, A. K.; Grest, G. S.; Hawker, C.; Janmey, P.; Kramer, E. J.; Nuzzo, R.; Russell, T. P.; Safinya, C. R.: Macromolecules at surfaces: Research challenges and opportunities from tribology to biology. J. Polym. Sci. B 2003, 41, 2755-2793.
 
    Addadi, L.; Safinya, C. R.: Biomaterials. Curr. Opin. Solid State Mater. Sci. 1997, 2, 325-329 (editorial overview).
 
    Safinya, C. R.: Biomolecular materials: structure, interactions and higher order self-assembly. Colloids and Surfaces A-Physicochemical and Engineering Aspects 1997, 128, 183-195.  
    Safinya, C. R.; Addadi, L.: Biomaterials. Curr. Opin. Solid State Mater. Sci. 1996, 1, 387-391 (editorial overview).
 
    Thomas, B. N.; Safinya, C. R.; Plano, R. J.; Clark, N. A.: Lipid Tubule Self-Assembly - Length Dependence on Cooling Rate through a First-Order Phase-Transition. Science 1995, 267, 1635-1638.
 
    Safinya, C. R.; Rothschild, K. J.: Self-Assembly and Protein Stability - Reply. Nature 1994, 370, 105-106.  
    Balsara, N. P.; Perahia, D.; Safinya, C. R.; Tirrell, M.; Lodge, T. P.: Birefringence Detection of the Order-to-Disorder Transition in Block Copolymer Liquids. Macromolecules 1992, 25, 3896-3901.
 
    Shen, Y.; Safinya, C. R.; Fetters, L.; Adam, M.; Witten, T.; Hadjichristidis, N., Macrolattice Formation in Amorphous Associating Polymers. Phys. Rev. A 1991, 43, 1886-1891.  
    Dimon, P.; Sinha, S. K.; Weitz, D. A.; Safinya, C. R.; Smith, G. S.; Varady, W. A.; Lindsay, H. M., Structure of Aggregated Gold Colloids. Phys. Rev. Lett. 1986, 57, 595-598.