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Safinya Group – Research Highlights

Chronological List of Research Highlights:

Gel-Expanded-Gel Condensed
Transition in
Neurofilament Networks
(Nature Materials 2010)		 Synchrotron SAXS Studies of
the Interactions of
Microtubules and Tau Protein
(Biophys. J. 2009)		 Transfection Enhancement
by Cholesterol and Analogs
(J. Phys. Chem. B 2009)
Cover of Gene Therapy Protocols
featuring the LC-Phases of
CL–DNA complexes
(Book Chapter)
Langmuir 2009 cover
Discovery of
Block Liposomes
(Langmuir 2009)		 Neurofilament Liquid
Crystalline Hydrogels
(Biophys. J. 2008)		 Custom multivalent
cationic lipids are superior
siRNA delivery agents
(Biochem. 2007)
News coverage featuring
the novel HIC phase of
CL–DNA complexes
(JACS 2006)
Invitation to the 2005 SSRL
User Meeting featuring
microtubule bundles and necklaces
(PNAS 2004)		 Universal transfection behavior
of lamellar CL-DNA complexes
of monovalent to pentavalent
cationic lipids
(J. Gene Med. 2005)

SSRL Science Highlight
Jan 2005 featuring
microtubule bundles
and necklaces
(PNAS 2004)

SSRL Science Highlight
Oct 2005 featuring
tubes from microtubule–
cationic lipid complexes
(PNAS 2005)
SSRL Science Highlight
Dec 2003 featuring
actin–α-actinin bundles
(PRL 2003) 		Confocal Imaging of
cellular pathways of
CL-DNA complexes
(Biophys. J. 2003)		 Science 2002:
News Focus on Drug Delivery
featuring CL-DNA complexes 		Chem. Eng. News 2000
(Jun 19): News of the Week
featuring cationic lipid-actin
complexes (Science 2000)
Phys. Today 2000
featuring Lipid-DNA complexes
as examples of
DNA inspired Electrostatics		 Science 2000:
Editor's Choice
featuring Cationic lipid-
Polypeptide complexes
(JACS 2000)		 Science 1998:
This Week in Science
featuring the inverse
hexagonal phase of
CL-DNA complexes
 (Science 1998) 		Science 1998:
Viewpoint
featuring
PEG-lipid hydrogels
Science 1997: Perspective
featuring formation of lamellar
CL-DNA complexes
(Science 1997)		 Science 1997:
TOC featuring the
lamellar structure of
CL-DNA Complexes
(Science 1997)		 Science 1996:
This Week in Science
featuring
PEG-lipid hydrogels
(Science 1996)		 Phys. Today 1995:
Special issue: X-rays
100 years later
Algebraic decay of pair
correlation function in a stack
of fluid membranes due to
the Landau-Peierls effect
Science 1994:
This Week in Science
featuring the
XSF apparatus
(Science 1994)		 Nature 1993: News and Views
Heat Proof Proteins
featuring heat-stable
layers of bacteriorhodopsin
(Nature 1993)

Science 1993:
This Week in Science
featuring lamellar
phases under flow
(Science 1993, PRL 1991)

 Science 1993:
This Week in Science
featuring a Flat Phase in
Red Blood Cell Skeletons
(Science 1993)
 
Phys. Today 1989:
Search & Discovery section
featuring Synchrotron x-ray
scattering studies of Helfrich
undulation forces in a stack of
fluid membranes (PRL 1986,
J. Phys. (Paris) 1988, PRL 1989)

Synchrotron x-ray studies
of freely suspended
stacked membranes:
structure of Lβ' phases
(PRL 1988, Science 1988,
JCP 1990)

Synchrotron x-ray studies
of freely suspended
discotic liquid crystal fibers
(PRL 1984)

  

Articles Featured on Journal Covers:

(Click on the cover for the article)
Langmuir 2008 Human Frontier Science
Program Journal 2008		 Biophys. J. 2007 Curr. Med. Chem. 2004
PRL 2003 Chem. Eng. News 2001
Cover Story on
Gene Delivery-
Without Viruses		 Chem. Eng. News 2000 Curr. Opin. Colloid
& Surface Sci. 1998

Selected Publications:

All  –  2006 to Present  –  1996 to 2005  –  1979 to 1995

Cytoskeleton - Cationic Lipid–NA Complexes - Lipid Membranes - Liquid Crystals - Others
 

Recent News Coverage of our Research:

UCSB News Releases

SSRL Highlights

Web Coverage of the HIC Honeycomb-Structure of Lipid-DNA Complexes (JACS 2006 PDF link)

Web Coverage of Lipid-Protein Nanotubes (PNAS 2005 PDF link)

Web Coverage of Microtubule "Living Necklaces" (PNAS 2004 PDF link)