There are numerous biased representations in traditional media, often depicting Latinos as conforming to negative ethnic stereotypes. Historically ingrained stereotypes devalue and derogate racial and ethnic minorities, causing minority members to feel negatively viewed by society. Encountering negative stereotypes can induce stigma-related stress for minorities. Current research examines whether stigmatizing negative stereotypes in the media has spill-over effects on neural systems related to incentive processing and motivated behavior. This study investigates how life stress modulates brain responses to rewards, focusing on whether contending with negative representations of one’s social group influences reward processing. Using functional magnetic resonance imaging (fMRI), we examined the effects of stigmatizing negative stereotypes on neural responses during the anticipation and consumption of monetary gains and losses in Mexican-American participants. Previous research has found that incentive-related patterns of brain activity within the nucleus accumbens differed significantly between Mexican Americans subjected to negative stereotypes and those who were not. This suggests that negative stereotypes can alter the neural mechanisms underlying reward processing. We are now aiming to extend this line of research recruiting participants with more diverse backgrounds. We predict that exposure to negative stereotypes would have a similar effect on a more diverse Latino population, leading to reduced motivation and altered decision-making.