The recent decade has witnessed the booming development of advanced porous materials (APMs) such as metal-organic frameworks (MOFs), covalent organic frameworks (COFs), porous organic polymers (POPs), and various molecular cages. Unlike their conventional counterparts (e.g., silica, activated carbon, zeolite), APMs have well-ordered structures, uniform yet tunable pore sizes, and versatile chemical compositions suitable for various modifications. Membrane technologies have attracted increased attention recently because of their important applications in clean energy and environmental sustainability. The combination of APMs in membrane technologies would generate innovative solutions and tremendous impacts on molecular separations. In this talk, I will present our group’s studies on APMs as membrane materials for gas and liquid separations, such as H2 purification, CO2 capture, and organic solvent nanofiltration.